COMMONLY USED DRUGS' DOSES IN PAEDS (GENERAL)

ANTI-PYRETICS

Syrup PCM 15mg/kg 4-6H
Syrup Ibuprofen (Brufen) 5-10mg/kg 4-8H

BRONCHIAL ASTHMA

IV Hydrocortisone 4mg/kg QID
Oral Prednisolone 1mg/kg OD
Monteleukast (Singulair) granules (NOT/kg)
<6y.o    4mg ON
6-14y.o 5mg ON
>14y.o  10mg ON
Neb Salbutamol 0.5cc + 3.5 cc 3% NS (2/4/6)hourly (<2 y.o)
Neb Salbutamol 1.0cc + 3.0 cc 3% NS (2/4/6)hourly (>2 y.o)
MDI salbutamol 4-6puff (<6y.o)
MDI salbutamol 8-12puff (>6y.o)

EPILEPSY

PR diazepam 0.2-0.5mg/kg
~2-5years 0.5mg/kg
~6-11 years 0.3mg/kg
~12years + 0.2mg/kg
IV diazepam 0.2mg/kg (slow bolus at 2mg/min; max 10mg)
IV phenytoin 20mg/kg (dilute in NS, max concentration at 10mg/ml; infuse at <1mg/kg/min)
IV midazolam 0.2mg/kg bolus (at 2mg/min, max 10mg), followed by infusion by infusion 3-5mcg/kg/min up to max of 15mcg/kg/min)
IV phenobarbitone 20mg/kg (max loading dose 1gram), infusion at 25-50mg/min, repeat hourly at 10mg/kg up to **100mg/kg/day until fits stop)
IV sodium valproate 20mg/kg bolus (max 1.25 gram over 1-5 min), followed by 1-5mg/kg/hour for 6-12 hours)

FEBRILE SEIZURES

PR diazepem  0.5mg/kg

INFLUENZA LIKE ILLNESS

Oseltamivir

Anti-viral treatment for >1year 
<15kg     60mg/day into 2 divided doses
16-23kg  90mg/day into 2 divided doses
24-40kg 120mg/day into 2 divided doses
>40kg    150mg/day into 2 divided doses

Anti-viral treatment for <1year
- recommended treatment dose for 5 days
<3months   20mg BD
3-5months  25mg BD
6-11monts  30mg BD

INOTROPES
IV dopamine        5-20mcg/kg/min
IV dobutamine     5-20mcg/kg/min
IV noradrenaline  0.05-0.5mcg/kg/min
IV adrenaline       0.05-0.5mcg/kg/min

KAWASAKI DISEASE
T. Aspirin 80mg/kg divided 4 doses for at least 2/52

MENINGITIS
IV cefotaxime 50mg/kg BD
IV ampicillin15-25mg/kg QID
IV Ceftriaxone (rocephine) 50mg/kg BD

NEPHRITIS / NEPHROTIC SYNDROME
T. Nifedipine 0.25-0.50mg/kg 6-8H
T. Frusemide (lasix) 1mg/kg
T. Captopril 0.1-0.5mg/kg TDS
T. Metoprolol 1-4mg/kg 12 H
Labetolol
0.2-1.0mg/kg/dose IV bolus, or
0.25-2.0mg/kg/hr by IV infusion
Penicillin V
1-5years - 125mg BD
6-12 years - 250mg BD
>12 years - 500mg BD
Human albumin (20-25%) at 0.5-1.0g/kg

PNEUMONIA
IV C-penicillin 50,000 IU/kg QID
IV azithromycin 15mg/kg OD - D1
IV azithromycin 7.5mg/kg OD - D2-D5
IV Augmentin 15-25mg/kg TDS
Syr Augmentin BD
IV Cefuroxime 25mg/kg TDS
Syr Cefuroxime (zinnat) 10-15mg/kg BD

SEDATION
Syr / PR Chloral hydrate 10mg/kg 6-8H
IV midazolam 0.1-0.2mg/kg
Infusion (ventilated): 3mg/kg in 50cc NS - run 1-4ml/hr ~1-4mcg/kg/min

SEPSIS
IV ceftriaxone 50mg/kg OD (severe infection)


TYPHOID
IV Ceftriaxone (Rocephine) 80mg/kg OD (till afebrile for 72H. NB - to continue Ab for at least 1/52 before deciding to change Ab)